Saturday, September 21, 2019

Information Systems Security Survey Essay Example for Free

Information Systems Security Survey Essay The University of Nebraska Medical Center (UNMC) is an institution that was built back in the 19th century. UNMC’s mission is to improve the health of Nebraska through premier educational programs, innovative research, the highest quality patient care, and outreach to underserved populations (UNMC, 2004). As an institution with key interest to privacy of its students, staff and subordinate staff, UNMC has adopted various policy guidelines to ensure information security system. The Information Security Management Plan (ISMP) describes its safeguards to protect confidential information. These safeguards are meant among another reason to: Ensure the confidentiality of data Ensure the integrity of data Ensure the availability of data Protect against anticipated threats or hazards to the security or integrity of the information UNMC has adopted information security industry best practices to implement its information security system (UNMC, 2014). They have become so effective that during 2011, a Hitrust Gap assessment was performed, and no significant gaps were found within its security program. The worksheet below outlines how these programs have been rolled out by different offices in the university. Worksheet: Information Security Program Survey Security Area Responsible Party / Office of Primary Responsibility Known Vulnerabilities / Risks Countermeasures / Risk Mitigation Strategy Acquisition (systems/services) Information Security Office Breach of the confidentiality clause All service providers must undergo an evaluation process to verify they are qualified. Contracts have a confidentiality clause whose breach terminates the contract. Asset management System Administrator Poor asset management Proper policies and procedure in place  to ensure effective asset management. Evaluation to ascertain the qualifications of asset managers. Audit and accountability Information Security Office Dishonest employees disclosing confidential information to third parties Every application contains a log that must be maintained to meet regulatory requirement. There is Information security Incident Response plan to handle any notable strange events. Authentication and authorization System Administrator Covered data may be transferred to third parties without authorization Employees are provided with user name and password to access the data. Employees are trained on developing a secure password. There are control policies in place governing access to this information. Business continuity Information Security Office Non-coordination and miscommunication between employees All employees are supposed to keep contact information of co-workers and supervisors to seek for help in case of any emergency. Compliance management Compliance Officer the Information Security Officer Employees failure to comply with the set guidelines, policies and procedure There is a compliance form that is filled before a major project is undertaken by the enterprise. The form is to ensure that no new risk is introduced to the enterprise. Configuration control System Administrator Compromised system security Every configuration must have a password. Each password must have at least ten characters. The password must be encrypted at all times. Data System Administrator Data may be intercepted during transmission Database with security keys is available to authorized employees only. Access to classified data is allowed to limited employees. Information security plan ensures security of covered data. Hardware System Administrator Destruction of hardware in disaster Only employees with technical know-how of operating hardware are allowed to use them. The hardware are encrypted for security purposes. Hardware backup system. Identity management Information Security Office Unauthorized covered data and information transfer through third parties Identity Management Program (IDM) outlines procedure for issuing credentials based on the NIST guidance. Checks are done on employees prior to their employment. Incident management Command Centre Incident Response Team Physical loss of data in a disaster An Incident Reporting and Response Plan is in place to report and respond to any  identified risk. Availability of a well-trained incident response team. Command Centre is established to manage emergency. Maintenance procedures Change Advisory Board (CAB) Existing patches within the security system A release process is in place to ensure that the changes do not affect non-primary system. Patching policies for workstations to ensure security. Media protection and destruction Information Security Office Unauthorized access covered data as well as information Data storage policies define how data stored in the media is to be protected. Data is only stored in a secured data centre or encrypted medium. Network System Administrator Unauthorized access to the network Network traffic is controlled by Cisco enterprise-class firewall where inbound connects are only allowed to DMZ. Internal trusted network is provided via an encrypted VPN tunnel. Technical perimeter is established to bar direct access from the internet to the Internal Trusted Area. Planning Information Security Office Poor planning that compromise management of the security system Contingency plan is in place to handle any eventuality. Employees are encouraged to store data on network file servers for backup. All backups are surely stored and marked for easy identification during emergencies. Personnel System Administrator Loss of data integrity Employees are only employed after exhibiting minimum security requirement. Information Security Addendum are to be signed for confidentiality purposes. An insider who ensures that all legal requirements are followed before access is granted must accompany outsiders accessing information. Physical environment System Administrator Physical safety of the environment may be compromised through attacks and burglary No unauthorized personal is allowed within the data centre premises. The data centers are controlled by keycard access. Policy Information Security Plan Coordinator Policies may be misinterpreted by the employee The University’s security policy is enshrined in the Privacy, Confidentiality and Security of Patient Proprietary Information Policy and the Computer Use and Electronic Information Security Policy. The two policies require that authorized people can only access this information. The policies are reviewed every two years to make them in tandem with the prevailing circumstances. Operations The Information Security Officer and the Infrastructure Team  Failure for operations to comply with the system security policy An operation must fill a compliance Checklist or a Security Risk Assessment form for review to verify that no new risk is introduced to the enterprise. Outsourcing System Administrator Unauthorized disclosure of security information by third parties Outsourced vendors must comply with UNMC Policy No. 8009, Contract Policy. Vendors accessing classified student information must sign the GLB Act contract addendum. Risk assessments Information Custodian Poor method of risk assessment that may downplay the actual impact of a risk Security assessment I conducted annually. All applications must meet the organizations security policies and procedure. Software System Administrator Software may be infected with a virus Software should not be installed unless the user trusts it. Vendor update and patches must be installed unless directed otherwise. Software license must be retained to get technical assistance. Training System Administrators and Information Custodians Misuse of security system Loss of data integrity Employees are trained on information security system before they are employed. System administrators and information custodians are annually trained on Specific Information Security Policy and Procedure. References UNMC. (March 2014) Strategic Plan 2010-2013. Retrieved from http://www.unmc.edu/wwwdocs/strategic-plan_06-10_v3-brochure1.pdf United States Government Accountability Office. (February 2010). ELECTRONIC PERSONAL HEALTH INFORMATION EXCHANGE: Health Care Entities Reported Disclosure Practices and Effects on Quality of Care. Retrieved from http://www.gao.gov/new.items/d10361.pdf UNMC. (February 9, 2004). Information Security Plan. Retrieved from http://www.unmc.edu/its/docs/UNMCInformationSecurityPlan-Sept2010.pdf

Friday, September 20, 2019

Features of a Financial Statement Analysis

Features of a Financial Statement Analysis TASK 1 Importance of Financial Statements All managers need to be able to interpret their company’s financial accounts as they hold valuable information about a wide range of factors that impact on the long term and short term profitability and stability of the company. By considering the various ratios below and, in particular, by drawing on trends between last year and the current position, it will be possible for the various division managers to identify where weaknesses lie and to determine what they can do in their own individual departments to improve the overall situation of the company (Fridson, 2002)[1]. Current Position of the Company In his statement, Robert assured management and staff that the company was in a â€Å"sound financial position†. A detailed review of the accounts has been undertaken, and all ratios are included in Appendix 1. Four key areas were looked at, across 2007 and 2008, as this is when the substantial changes occurred. These changes are profitability, efficiency, liquidity and stability, all of which are important to the company. Profitability has fallen dramatically between 2007 and 2008. The gross profit margin figure shows the company’s ability to control the costs of the goods that it produces. Although sales volumes could alter, it would be expected that the profit margins obtained would not alter dramatically. In 2008, gross profit margins were 36.33%, substantially less than the margins of 42.21% in 2007, which suggests that the cost of producing each item is increasing at an unacceptable level. The operating profit gives more information on how the company manages its overheads; these figures have also dropped significantly (from 20.57% to 10.56%). This is clearly partly down to the reducing gross profit margin, but also indicates that overheads are becoming increasingly problematic for the company, in terms of relative costs (Helfert, 2001)[2]. Efficiency ratios indicate how well the company is using its resources, both fixed and working capital. The ratio in relation to the efficiency of capital employed has dropped from 4.05 to 3.51, showing that the company has lost a considerable amount of efficiency in its operations and is not producing the same output with the capital employed as it was in 2007 (Friedlob, 2003)[3]. Liquidity ratios are incredibly important as these reveal the company’s ability to meet its current liabilities. Poor liquidity could cause immediate and massive problems for the company because it indicates that it will be unable to pay its debts as they fall due. The current ratio shows the ability of the company to meet all current liabilities with all current assets that it holds. In both 2007 and 2008, the figure was well in excess of the 1:1 cover, although it did drop from 2.00 to 1.70, which could be indicative of a downward trend in the company and should be looked at regularly in order to ensure that the figure does not drop further. More worrying is the quick ratio figure. This shows how readily the cash and easily available current assets could meet the current liabilities. A ratio of 1:1 is also desirable, yet the company had a ration of 0.38 in 2007, dropping to 0.12 in 2008. This suggests that much of its current asset inventory is held in non-readily convertibl e assets such as stock (Towsey, 1974)[4]. Stability ratios reveal the amount of long term debt a company is in and, where this company is concerned, the gearing has been consistently low, showing that there is not a great risk within the way the company is financing itself. Conclusions Robert was correct in stating that he felt the company was stable in the long term; however, there are considerable short term concerns, particularly in relation to liquidity, which need to be addressed urgently if the company is not to suffer short term issues. TASK 2 The Balanced Scorecard Kaplan and Norton (1993)[5] developed the concept of the balanced scorecard, which was initially created as a means of assisting management with their strategic planning. The model is two-fold, the first purpose being to improve the communications for the company (both internally and externally) and the second to assist managers in ensuring that their goals are reached. The balanced scorecard model forwarded by Kaplan and Norton works on assisting managers in having a clear strategic goal and in ensuring that the activity needed to achieve these goals is put into action, throughout the organisation. This process recognises that it is not possible simply to look at a company’s financial performance and from this to derive a set of actions that should be undertaken to improve performance, in future years. There is generally a time lag, when it comes to company performances, with inputs such as investment in machinery taking at least a few months to be seen in the financial returns. Kaplan and Norton encouraged companies to take a different approach and to look firstly at the inputs that management could make directly into the company. It is these factors that should be measured and, provided the correct strategic goal has been established, achieving these individual goals by management should ensure that the ultimate goals in terms of financial performance are met (Niven, 2006)[6]. Companies are encouraged to look at their businesses from four different perspectives when establishing their strategic goals: financial, customer, internal process and innovation and learning. The financial perspective is the one traditionally considered by organisations and includes factors such as profit growth and revenue. The management should, however, be encouraged to take a longer term view when setting strategic goals. The customer perspective is crucially important as it looks at the way the customer perceives the company and any possible changes to the customer perspective that would be needed for the company to achieve its ultimate strategic goals. Internal processes look at the way the company is run internally and how these can be adapted to help achieve the long term goals and are often related to the customer perspective, e.g. quicker lead times or more readily available stock. Finally, there is the innovation and learning aspect which directly leads into the long term growth by ensuring that the company is constantly looking for new ways of doing things, which either include efficiency savings or a better customer experience (Kaplan, 2004)[7]. The Development of Intangible Assets Introduction Intangible assets are those assets within the company that are often overlooked such as the knowledge base of the staff or the underlying strength of the information systems. When considering the intangible assets, this largely refers to the learning and innovation perspective within the balanced scorecard and can be broken down to look at jobs, i.e. the human capital and relevant expertise these individuals have, the systems capital which refers to the information systems within the company and the organisational capital which refers to the climate in which the company operates, i.e. the market place in which it is based (Wall, 2003)[8]. Intangible assets within the company Critically, the company mainly needs to consider both its human capital and its information systems. In relation to its human capital, the company has significant difficulties with its turnover, particularly within the packing division. With a high turnover of staff, it is difficult to maintain efficiency and quality in the products and makes innovation difficult as members of staff are unprepared to take a long term view. The technical department is clearly important when it comes to ensuring the maximum efficiency of the machines. Therefore, the turnover rate of 18% in relation to technicians and the seeming difficulty in recruiting new technicians is an issue that has to be looked at closely by management. Information systems are outdated within the company. Computer technology is not used adequately to ensure that information is shared between the sites. Failure to share information will result in wastage and unnecessary expenses as well as large overheads (a problem that the company has, as identified previously). Furthermore, no information is collected in relation to customer satisfaction which makes the task of improving and managing customer perceptions impossible. A fully integrated and operational information system is needed to improve both efficiency of production and customer satisfaction. How can these factors be developed? The first concern must be in relation to the employees. There is a substantial turnover of staff, averaging 12%. Direct operations have a turnover rate substantially below this, at just 5%. Critically, the direct operations and production teams have a structure of bonus payments which is generous and allows staff to receive extra payments as they become more efficient, thus encouraging staff to stay longer in their roles. Whilst the packing team recognises that it is generally less skilled, there is no incentive in relation to performance and there is clearly very little in the way of employee loyalty (evidenced by the way in which the staff shop is used). Consideration should be given to implementing a similar bonus scheme for the packers, as this would not only reduce staff turnover in the packing department but would also encourage better quality of work (Harvard Business School Press, 2005)[9]. Issues such as more flexible working patterns should be considered as the majority of the packers are female and, therefore, issues such as childcare are much more likely to be important to this section of the workforce. Benefits such as childcare vouchers may also be a good way of improving retention. Due to the skilled nature of the technicians’ role, advertisements should be placed further afield. Workers are often prepared to travel and by widening the search area the company may locate better skilled and more loyal staff for the important technical department. Investment is needed in the information technology systems. They are six years old and do not offer the necessary level of service. The systems, particularly in relation to sharing technical knowledge, must be integrated and additional automation would be beneficial to the ultimate efficiency of the company. There are also considerable uncertainties in relation to factors such as stock levels, work in progress, production costs, all of which are vital and need to be integrated into the information system (Kaplan, 2001)[10]. Conclusions In order to develop the intangible assets of the company, the focus must necessarily be on dealing with the issues in relation to employee retention and productivity as well as ensuring that the information systems adequately support the company moving forward. Both of these factors will require investment, but should amply pay for themselves, in the long run. TASK 3 Inventory Management Inventories refer to all goods and stocks held by the company, whether they are complete or not. As this is a manufacturing company, it would be anticipated that the level of inventory is rather high. However, even with this assumption, the total amount of stock being held by the company has risen dramatically to  £3,915,000 in 2008, from just  £2,765,000 in 2006 and is rightly a cause for concern by management (Mercado, 2007)[11]. Importance of Inventory This is not the only company to underestimate the importance and potential impact of inventory on the financial position of the company as a whole. A certain level of inventory is essential as the company relies on suppliers (of varying reliability) and, therefore, must build in a time lag between when the supplier delivers the material and when the goods actually leave the company. As well as the time lag, there are natural uncertainties which mean that a certain amount of stock must be held, particularly to deal with issues such as special offers from some of the larger retailers. There are also economies of scale to be had and it will be more profitable for the company to purchase material in bulk and to transport finished products in bulk (Koumanakos, 2008)[12]. Whilst all of these reasons for maintaining an inventory are valid, it is important to recognise that having too much in the way of inventory is potentially negative on the financial position of the company. The ratios suggesting problems with short term liquidity are indicative of this high level of inventory. Too much of the company’s cash is tied up in the stock, meaning that the company may not be able to meet its commitments to short term creditors. Working capital should also be of considerable interest to the company as it is another reflection of the short term liquidity of the company and is a way of looking at whether or not the company can meet its short term liabilities and operating expenses (Wild, 2002)[13]. Accounting for Inventory A vitally important way of managing and measuring working capital is to look at how many days it takes from the point at which money is paid out for the raw materials to the point when the company receives money in for the finished products. This length of time should, ideally, be as short as possible so at to ensure that the company gets a return on its products as quickly as possible. Reducing this time involves either extending the length of time it takes to pay suppliers, shortening the length of time it takes to collect money from customers or reducing the time it takes to manufacture the goods. This period of time is calculated by adding the inventory conversion period to the receivables conversion period and taking away the payables conversion period (each measured in days). The inventory conversion period is the inventory divided by the cost of goods sold multiplied by 365; the receivables conversion period is the receivables divided by sales multiplied by 365; and the payables conversion period is accounts payable divided by cost of goods sold multiplied by 365 (Toomey, 2000)[14]. By using the inventory figures for this calculation, it is easy to see whether or not the period of time is increasing and at which point there seems to be a blockage in the throughput. In the case of the company, it is clear to see that the amount of stock being kept is increasing; raw material inventory has only gone up a slight amount. However, the amount of bought-in finished goods that are being held has dramatically increased and should be an area that the management team concentrates on (Harrington, 1990)[15]. It is also worth bearing in mind that there are costs inherent with storing excess stock. It has already been recognised that overhead costs are in excess of what they should be for the company and are growing rapidly. These will almost certainly be related, at least partially, to the trend towards storing more stock. Conclusion Inventory management, despite being an issue for management teams to control, has a direct and substantial impact on the company’s financial accounts. Holding too much stock will be evident in terms of the current asset figures on the balance sheet, but also in the profit statement (Jones, 1985)[16]. Potential savings in reducing the amount of stock that is held can come not only from the availability of cash for other activities (such as meeting short term liabilities), but also in terms of ensuring that overhead costs such as storage are kept to a minimum. These factors must be considered by the management team as a matter of priority. TASK 4 Introduction Before introducing any new product, it is important that the management team consider all of the possible impacts of this introduction, both financially and practically. In this case, for example, it should also be considered that the HC007 is a new and improved version of the HC003 and the company wishes to develop a reputation for producing leading edge technology. Bringing in a new product such as this will naturally increase the company’s profile in the market and should not be disregarded as a benefit when analysing the raw figures in relation to the possible move (Rainey, 2005)[17]. The company should also consider the current level of inventory that is held in relation to HC003, both in terms of completed products and work in progress, as this may result in financial losses to the company, if these items cannot be sold on (Wilson, 2005)[18]. Theories of Product Appraisal A key way of determining the potential viability of the new product is to consider the breakeven point which will tell the company, based on the proposed sales value, how many products would have to be sold before the costs of production are covered. The breakeven point is established by taking the fixed costs and dividing them by the selling price, minus the variable costs. Therefore, in the case of the HC007, the fixed costs are thought to be 24,000 divided by 12 (18 – 6) making 2,000. On the assumption that the fixed and variable costs are the same for the HC003, the breakeven point for this would be 24,000 divided by 10 (16 – 6), making 2,400, which it is currently comfortably achieving (Daly, 2002)[19]. There are weaknesses in using this analysis. It assumes that the variable costs are constant for every unit of output and that there are no economies of scale involved. It also assumes that fixed costs are constant and would be incurred regardless of the level of production. Finally, there is the assumption that there is no wastage, i.e. all products produced are sold. This is unrealistic, as there is likely to be at least some degree of leakage. Analysis of the Hedge Clipper HC007 HC007, on the assumption that the full 4,000 prospective sales are made, would produce a total profit of 24,000. HC003, on the assumption that 3,500 units were sold, would achieve a total profit of 17,500. On the face of it, therefore, the new product HC007 would be a worthwhile addition to the product range. It should be noted that the nature of fixed costs means that they are going to be incurred, regardless of whether or not the HC007 is launched and should not, therefore, play any part in the decision making process. If this theory is followed, the profit margin on the HC007 would be 12, whereas working with the same numbers the gross profit margin for the current HC003 would be 11. This is the contribution available, through the production of these products to meet fixed costs. There is no substantial difference between the two and consideration should be given as to whether there could be a better use of the resources available within the company (Groth, 1996)[20]. An absorption or recovery rate of 300% seems incredibly high and consideration should be given as to whether the overheads in this particular area of production are viable. With such high overhead rates, there may be more productive ways to produce a profitable item, either through the use of automation or through better use of premises’ space (Kuczmarski, 1992) [21]. Careful consideration should also be given as to the prospective number of sales. The company is currently selling 3,500 hedge cutters and has predicted that the new model would generate sales of 4,000 hedge cutters. This suggests that 500 people would be expected to purchase the new product, purely because it is new and innovative. Conclusions Appraising a new product is not simply about seeing whether a company can sell the product for more than it costs to produce the product. Issues such as other opportunities that the company may be foregoing in order to produce this product need careful consideration. It is not about producing a profitable item; it is about producing the most profitable item (Constantineau, 1992)[22]. In this case, the company needs to ensure that the sales predictions are accurate and that there is no other potential new product line that would serve the company better. Appendix 1 Footnotes [1] Fridson, M.S. Alvarez, F., 2002. Financial Statement Analysis: A Practitioners Guide.  John Wiley and Sons. [2] Helfert, E.A., 2001. Financial Analysis: Tools and Techniques : a Guide for Managers. McGraw-Hill Professional. [3] Friedlob, G.T. Schleifer, L.L.F., 2003. Essentials of Financial Analysis. John Wiley and Sons. [4] Towsey, R.G., 1974. The use of operating ratios in retail management . International Journal of Retail Distribution Management, 2, 4. [5] Kaplan, R.S. Norton, D.P., 1993. Putting the Balanced Scorecard to Work. Harvard Business Review, Sep – Oct, pp. 2-16. [6] Niven, P.R., 2006. Balanced Scorecard. Step-by-step. Maximizing Performance and Maintaining Results. 2nd ed., John Wiley Sons. [7] Kaplan, R.S. Norton, D.P., 2004. Strategy maps: Converting intangible assets into tangible outcomes. Boston: Harvard Business School Press. [8] Wall, A., Kirk, R. Martin, G.,2003. Intellectual Capital: Measuring the Immeasurable?  Elsevier. [9] Harvard Business School Press, 2005. Retaining Your Best People. Harvard Business School Press. [10] Kaplan, R.S. Norton, D.P., 2001. The Strategy-focused Organization: How Balanced Scorecard Companies Thrive in the New Business Environment. Harvard Business Press. [11] Mercado, E.C., 2007. Hands-On Inventory Management. CRC Press. [12] Koumanakos, D.P., 2008. The effect of inventory management on firm performance. International Journal of Productivity and Performance Management, 57, 5. [13] Wild, T., 2002. Best Practice in Inventory Management. Institute of Operations Management,  Butterworth-Heinemann. [14] Toomey, J.W., 2000. Inventory Management: Principles, Concepts and Techniques. Springer. [15] Harrington, T.C., Lambert, D.M. Vance, M.P., 1990. Implementing an Effective Inventory Management System. International Journal of Physical Distribution Logistics Management, 20, 9. [16] Jones, T.C., Riley, D.W., 1985. Using Inventory for Competitive Advantage through Supply Chain Management. International Journal of Physical Distribution Logistics Management, 15, 5. [17] Rainey, D.L., 2005. Product Innovation: Leading Change Through Integrated Product Development. Cambridge University Press. [18] Wilson, R.M.S. Gilligan, C., 2005. Strategic Marketing Management: Planning, Implementation and Control. Butterworth-Heinemann. [19] Daly, J.L., 2002. Pricing for Profitability: Activity-Based Pricing for Competitive Advantage. John Wiley and Sons. [20] Groth, J.C. Byers, S.S., 1996. Creating value: economics and accounting perspectives for managers. Management Decision, 34, 10. [21] Kuczmarski, T.D., 1992. Screening potential new products. Strategy Leadership, 20, 4. [22] Constantineau, L.A., 1992. The Twenty Toughest Questions for New Product Proposals. Journal of Consumer Marketing, 9, 2.

Thursday, September 19, 2019

Genital Herpes Essay -- essays research papers

  Ã‚  Ã‚  Ã‚  Ã‚  I have infected 45 million Americans and will infect 1 million more Americans each year. Who am I?   Ã‚  Ã‚  Ã‚  Ã‚  Herpes, from the ancient Greek meaning to creep or crawl, is the name of a family of viruses of which herpes simplex virus 1 and herpes simplex virus 2 (HSV-1 and HSV-2) are the most serious human pathogens. HSV-1 is normally associated with orofacial infections and encephalitis, whereas HSV-2 usually causes genital infections and can be transmitted from infected mothers to neonates. Both viruses establish latent infections in sensory neurons and, upon reactivation, cause lesions at or near point of entry into the body. While HSV-1 and HSV-2 are different viruses, under a microscope, HSV-1 and 2 are virtually identical, sharing approximately 50% of their DNA and are treated similarly. HSV-1 and HSV-2 contain a large double-stranded DNA molecule. HSV is gram negative, consists of 162 capsomers and replication takes place within the nuclei of eukaryotic cells. The HSV virion has four parts: an electrondense core containing viral DNA; an icosapentahedral capsid; a tegument-an amorphous layer of proteins that surround the capsid; and an envelope. HSV-1 and HSV-2 encode at least 84 different polypeptides. Each protein does many things, hence HSV genes can encode several hundred different functions. To initiate infection, HSV attaches to at least three different classes of cell-surface receptor and fuses its envelope with the plasma membrane. The capsid, minus its envelope, is transported to the nuclear pore, through which it releases viral DNA into the nucleus. HSV replicates by three rounds of transcription that yield: alpha (immediate early) proteins that mainly regulate viral replication; beta (early) proteins that synthesise and package DNA; and gamma (late) protei ns, most of which are virion proteins. Of the 84 known polypeptides, at least 47 are not needed for viral replication in cultured cells. These 47 genes are not completely dispensable. Some complement cellular genes that are not expressed in terminally differentiated cells; others alter cellular metabolism to ensure high virus yields. Mutant viruses lacking these genes cannot survive in nature.   Ã‚  Ã‚  Ã‚  Ã‚  The symptoms of genital herpes vary widely form person to person. Some people have severe symptoms (such as many painfu... ...Unlike the culture method, this test does not require growing the virus but rather seeks to identify herpes by the presence of antigens, fragments of the virus that are know to stimulate the immune response. Herpes cannot be cured. Once someone is infected with either virus, it cannot be cleared from the human body. Genital herpes is usually treated with antiviral drugs such as Acyclovir (Zovirax), Famciclovir (Famvir), and Valacyclovir (Valtrex) to help keep the virus in an inactive state and prevent most outbreaks but again does not cure a person from the virus. During an active herpes episode people should follow a few key steps to speed healing and avoid spreading the infection to other places on the body or to other people:  ·Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Keep the infected area clean and dry to prevent other infections from developing  ·Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Try to avoid touching the sores  ·Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Wash you hands after contact with the sores  ·Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Avoid sexual contact from the time the first symptom is felt until the sores are completely healed, that is, the scab has fallen off and new skin has formed where the sore was.

Wednesday, September 18, 2019

The Connections Between Artificial Intelligence and Other Fields Essay

The Connections Between Artificial Intelligence and Other Fields. Abstract Through examples from several fields, this paper will describe the connections between Artificial Intelligence and other areas. Some of these areas make great contributions to AI research, others gain knowledge and technique from that same AI research. This paper will further detail the incredible capacity of AI research to be applied elsewhere to solve similar problems. The goal of this paper is to describe to the reader the impact that AI can create on seemingly unrelated fields. Introduction While Ginsberg defines artificial intelligence as "the enterprise of constructing a physical-symbol system that can reliably pass the Turing test", it is about much more than that (Ginsberg 8). It is about creating a solution where one may not have existed, and eventually programming a machine to do the same. This incredible capacity to find solutions is what AI offers to so many other fields. Artificial intelligence research is not tied to the fields of engineering, psychology, or even computer science. The techniques used in AI have found uses within a large number of other fields. Within the course of this paper, the elements of AI will be outlined, and the way in which they benefit other fields will be explored. Several examples of these fields will be described, and the way in which they incorporate AI will be discussed. Two or three of these fields will be discussed in much greater depth in the second paper, to be completed before December 5th. The reason that artificial intelligence is such a popular field for use by others is that it does not cater to an incredibly specific audience. One of the principle goals of AI research is to help prepare a .. ...ork), and not on theoretical AI. As the technology advances, and more and more lives depend on computers, I can only predict that the reach of AI influences will widen, until it eventually benefits all of us. Bibliography- BotSpot "The Spot for All Bots on the Net", http://www.botspot.com/main.html, Visited Nov. 3 1997 Dankel, Dr. Douglas D. CAP6635 lectures and lecture notes. (Numbered by slide), Fall semester 1997 Ginsberg, Matt; Essentials of Artificial Intelligence, Morgan Kaufman Publishers, San Francisco; 1993 Interactive Systems Labs - JANUS project, http://www.is.cs.cmu.edu/ISL.speech.janus.html, Visited Nov. 3 1997 Interactive System Labs - Speech Recognition, http://www.is.cs.cmu.edu/ISL.speech.recog.html, Visited Nov. 3 1997 Pittsburgh Area Cognitive Tutoring (PACT), http://sands.psy.cmu.edu/ACT/awpt/algebra-home.html, Visited Nov. 1 1997

Tuesday, September 17, 2019

Are Cell Phones Necessary in Teen’s Lives? Essay

I believe that cell phones are necessary in teen’s lives for the following three reasons. Firstly, they are a good social way to keep in contact with friends and family. Secondly, they are a fast and easy emergency resource. Thirdly, cell phones are an easy way to access the internet and they are entertainment to teens. Firstly, I believe that cell phones are a good social way to keep in contact with friends and family for the following three reasons. A lot of teen’s need to keep in touch with their family and friends so they can know whether or not they have anything after school. Having a cell phone makes it easy for teen’s to talk to their friends and family on any day at any time. Lastly, if there is a sudden change with any plans they have, having a cell phone makes it easy to keep in contact. Therefore, for those reasons I believe cell phones are necessary in teens lives. Secondly, I believe that cell phones are a fast and easy emergency resource for teens for the following three reasons. One of the reasons is if there is an emergency at home if is easy to get in contact with their kids. Another reason is sometime when teenagers are walking home alone and they feel as if they were being followed they sometimes pretend to act as if they were on talking to someone. Lastly, sometimes teenagers leave their school work at home they can easily text or call their parents and get them to bring their project to them. Therefore, for those reasons I believe cell phones are necessary in teen’s lives. Lastly, I believe that cell phone are an easy way to access internet and are entertainment for teens. One of the reasons is that cell phones have easy access to social networking sites. Sites like Facebook and Twitter can be used very accessible anywhere you go. Another reason is most phones have an application world, which allows them to pick from thousands of different applications to customize their phone. Lastly, with Wifi you can use the internet to go on any site at any time. Therefore, that is another reason why I believe cell phones are necessary in teens lives. In conclusion, I believe that cell phones are necessary in teen’s lives for the following three reasons. Firstly, they are a good social way to keep in contact with friends and family. Secondly, they are a fast and easy emergency resource. Thirdly, cell phones are an easy way to access the internet and they are entertainment to teens.

Monday, September 16, 2019

Hitler’s Anti-Semitic Ideas and Medical Experiments

In the 1930’s, during the Great Depression, Hitler was presented with an opportunity to persuade the German public of his anti-Semitic ideas through the use of propaganda. This was an easy task for Hitler to accomplish with the morale of the country already low after their defeat in World War I, 15 years prior. Germany was reeling from the effects of the New York stock market crash and the German people were seeking a leader who inspired confidence and would return hope for a better future. All of these factors gave Hitler’s ideas the perfect opportunity to germinate and take root in the minds of the citizenry. Hitler’s hatred was not limited to the Jewish community. Jews were only but one of the racially targeted groups that the Nazi Party sought to exterminate. Gypsies, the handicapped, homosexuals, Jehovah Witnesses, and the Poles were also considered to be threats to Hitler’s cause. Additionally, the Nazi’s persecution extended to political opponents such as the Communists, Socialists, Social Democrats, and trade union leaders. Preceding Hitler’s rise to power in 1933, German anthropologists, psychiatrists, and geneticists were already researching and studying racial hygiene and eugenics. These medical professionals embraced the Nazi regime who supported their study of eugenics. Scientists were attempting to prove that there was a genetic link within the superior race that would have justified Hitler’s purging of the inferior being from the nation. German scientists needed political backing for government funding and the Nazi regime needed the scientists to legitimatize their policies of anti-Semitism. It was the perfect marriage that resulted in the prefect storm. As World War II began and the Third Reich’s anti-Semitic views continued to infect the country, the German scientists worked diligently to prefect the Master Race through experimentation of those deemed degenerate by the Nazi Regime. In October of 1939, the Nazi’s initiated Action T4 (short for Tiergartenstra? e 4), or more commonly known as the Euthanasia Program. This program was the result of a petition received by the parents of a German child born with severe disabilities requesting Hitler’s permission to have the child put to death. Hitler approved the deliberate murder of the child and authorized the creation of the Reich Committee for the Scientific Registering of Serious Hereditary and Congenital Illnesses which would oversee the approval of future applications to put children in similar circumstances to death. Soon the Euthanasia Program was extended to adults with physical and mental disabilities as well. Anyone deemed unworthy of life was murdered as part of the T4 Program as the Nazi’s attempted to cleanse the German people of racially unsound elements. In addition to the T4 Program, many painful and inhumane of experiments were performed on the gypsies, the handicapped, homosexuals, Jehovah Witnesses, and the Poles. Experiments were done by physicians from the German air force and from the German Experimental Institution for Aviation in hopes of prolonging the survival of Axis military personnel. These experiments consisted of the use of a low-pressure chamber to determine the maximum altitude from which crews of damaged aircraft could parachute to safety. Freezing experiments were also done on concentration camp prisoners in hopes of finding an effective treatment for hypothermia. One experiment at Dachau was conducted to study various methods of making sea water drinkable. Many Roma gypsies were deprived food and given nothing but sea water to drink and died from dehydration as a result of this experiment. Experiments were also done to determine ways to effectively treat injured German military and occupation personnel with pharmaceuticals. Scientists used concentration camp prisoners as guinea pigs to test immunization compounds comprised of sera for the prevention and treatment of infectious diseases such as malaria, typhus, tuberculosis, typhoid fever, yellow fever, and infectious hepatitis. Bone grafting experiments were also done to test a new drug called sulfanilamide. Phosgene and mustard gas were tested on some prisoners as possible antidotes. Josef Mengele performed infamous experiments used in perfecting the Nazi’s idea of the â€Å"Master Race. Mengele conducted medical experiments on twins at the concentration camp of Auschwitz. The twins would be thoroughly measured, shaved, and photographed. They were forced to sit in vats of hot water until they passed out and would be photographed again. The twins also received hot water enemas and would be forced to suffer through painful and humiliating urological examinations. After all of these examinations were complete, the twins would be put to death by an injection in the heart and dissected for further research. In addition to these heinous experiments he also directed serological experiments on Roma gypsies, as did Werner Fischer at Sachsenhausen, in order to determine how different â€Å"races† withstood various contagious diseases. Further experiments were done in the study of sterilization to determine a cost effective way to easily sterilize those that the Nazi’s determined were racially inferior. Between the Nazi’s rise to power and their strong anti-Semitic teachings coupled with the studies already in progress by German geneticists, psychiatrists, and anthropologists the medical experiments performed during World War II were inevitable. The experiments that took place on prisoners of the concentration camps were clearly not limited to the Jews. In order for the scientists to prove their theories on racial hygiene the experiments had to be conducted on each of the races and groups that were regarded as inferior. This resulted in the gypsies, the handicapped, homosexuals, Jehovah Witnesses, and the Poles falling victim to the same experiments that were conducted on the Jews in hopes of creating the â€Å"Master Race. †

Sunday, September 15, 2019

Carrie Chapter Thirteen

She had done it; that was enough; she was satisfied. (maybe he'll fall in love with her) She looked up as if someone had spoken from the hallway, a startled smile curving her lips. That would be a fairy-tale ending, all right. The Prince bends over the Sleeping Beauty, touches his lips to hers. Sue, I don't know how to tell you this but The smile faded. Her period was late. Almost a week late. And she had always been as regular as an almanac. The record changer clicked; another record dropped down. In the sudden, brief silence, she heard something within her turn over. Perhaps only her soul. It was nine-fifteen. Billy drove to the far end of the parking lot and pulled into a stall that faced the asphalt ramp leading to the highway. Chris started to get out and he jerked her back. His eyes glowed ferally in the dark. ‘What?' she said with angry nervousness. ‘They use a P.A. system to announce the King and Queen,' he said. Then one of the bands will play the school song. That means they're sitting there in those thrones, on target.' ‘I know all that. Let go of me. You're hurting.' He squeezed her wrist tighter still and felt small bones grind. It gave him a grim pleasure. Still, she didn't cry out She was pretty good. ‘You listen to me. I want you to know what you're getting into. Pull the rope when the song is playing. Pull it hard. There will be a little slack between the pulleys, but not much. When you pull it and feel those buckets go, run. You don't stick around to hear the screams or anything else. This is out of the cute-little-joke league. This is criminal assault, you know? They don't fine you. They put you in jail and throw the key over their shoulder.' It was an enormous speech for him. Her eyes only glared at him, full of defiant anger. ‘Dig it?' ‘Yes.' ‘All right. When the-buckets go, I'm going to run. When I get to the car, I'm going to drive away. If you're there, you can come. If youre not, I'll leave you. If I leave you and you spill your guts, I'll kill you. Do you believe me' ‘Yes. Take your fucking hand off me.' He did. An unwilling shadow-grin touched his face. May. ‘It's going to be good.' They got out of the car. It was almost nine-thirty. Vic Mooney, President of the Senior Class, was calling jovially into the mike.. ‘All right, ladies and gennelmen. Take your seats, please. Ifs time for the voting. We're going to vote for the King and Queen.' ‘This contest insults women!' Myra Crewes called with uneasy good nature. ‘It insults men, too!' George Dawson called back, and there was general laughter. Myra was silent. She had made her token protest. ‘take your seats, please!' Vic was smiling into the mike, and blushing furiously, fingering a pimple on his chin. The huge Venetian boatman behind him looked dreamily over Vic's shoulder. ‘Time to vote.' Carrie and Tommy sat down. Tina Blake and Norma Watson were circulating mimeographed ballots, and when Norma dropped one at their table and breathed ‘Good LUCK!' Carrie picked up the ballot and studied it. Her mouth popped open. ‘Tommy, we're on here!' ‘Yeah, I saw that,' he said. ‘The school votes for single candidates and their dates get sort of shanghaied into it. Welcome aboard. Shall we decline?' She bit her lip and looked at him. ‘Do you want to decline?' ‘Hell, no,' he said cheerfully. ‘If you win, an you do is sit up there for the school song and one dance and wave a sceptre and look like a goddam idiot. They take your picture for the yearbook so everyone can see you look like a goddam idiot.' ‘Who do we vote for?' She looked doubtfully from the ballot to the tiny pencil by her boatful of nuts. ‘They're more your crowd than mine.' A chuckle escaped her. ‘In fact, I don't really have a crowd.' He shrugged. ‘Let's vote for ourselves. To the devil with false modesty.' She laughed out loud, then clapped a hand over her mouth. The sound was almost entirely foreign to her. Before she could think, she circled their names, third from the top. The tiny pencil broke in her hand, and she gasped. A splinter had scratched the pad of one finger, and a small bead of blood welled. ‘You hurt yourself?' ‘No.' She smiled, but suddenly it was difficult to smile. The sight of the blood was distasteful to her. She blotted it away with her napkin. ‘But I broke the pencil and it was a souvenir. Stupid me.' `There's your boat,' he said, and pushed it toward her. ‘Toot, toot.' Her throat closed, and she felt sure she would weep and then be ashamed. She did not, but her eyes glimmered like prisms and she lowered her head so he would not see. The band was playing catchy fill-in music while the Honour Society ushers collected the folded-over ballots. They were taken to the chaperones' table by the door, where Vic and Mr Stephens and the Lublins counted them. Miss Geer surveyed it all with grim gimlet eyes. Carrie felt an unwilling tension worm into her, tightening muscles in her stomach and back. She held Tommy's hand tightly. It was absurd, of course. No one was going to vote for them. The stallion, perhaps, but not when harnessed in tandem with a she-ox. It would be Frank and Jessica or maybe Don Farnham and Helen Shyres. Or – hell! Two piles were growing larger than the others. Mr Stephens finished dividing the slips and all four of them took turns at counting the large piles, which looked about the same. They put their heads together, conferred, and counted once more. Mr Stephens, nodded, thumbed the ballots once more like a man about to deal a hand of poker, and gave them back to Vic. He climbed back on stage and approached the mike. The Billy Bosman Band played a flourish. Vic smiled nervously, harrumphed into the mike, and blinked at the sudden feedback whine. He nearly dropped the ballots to the floor, which was covered with heavy electrical cables, and somebody snickered. ‘We've sort of hit a snag,' Vic said artlessly. ‘Mr Lublin says this is the first time in the history of the Spring Ball-‘ ‘How far does he go back?' someone behind Tommy mumbled. ‘Eighteen hundred?' ‘We've got a tie.' This got a murmer from the crowd. ‘Polka dots or striped?' George Dawson called, and there was some laughter. Vic gave a twitchy smile and almost dropped the ballots again. ‘Sixty-three votes for Frank Grier and Jessica MacLean, and sixty-three votes for Thomas Ross and Carrie White.' This was followed by a moment of silence, and then sudden, swelling applause. Tommy looked across at his date. Her head was lowered, as if in shame, but he had a sudden feeling. (carrie carrie carrie) not unlike the one he had had when he asked her to the prom. His mind felt as if something alien was moving in there, calling Carrie's name over and over again. As if ‘Attention!' Vic was calling. ‘If I could have your attention, please.' The applause quieted. ‘We're going to have a run-off ballot. When the people passing out the slips of paper get to you, please write the couple you favour on it.' He left the mike, looking relieved. The ballots were circulated; they had been hastily torn from leftover prom programmes. The band played unnoticed and people talked excitedly. ‘They weren't applauding for us,' Carrie said, looking up The thing he had felt (or thought he had felt) was gone ‘It couldn't have been for us.' ‘Maybe it was for you.' She looked at him, mute. ‘What's taking it so long?' she hissed at him. ‘I beard them clap. Maybe that was it. If you fucked up-‘ The length of jute cord hung between them limply, untouched since Billy had poked a screwdriver through the vent and lifted it out. ‘Don't worry,' he said calmly. ‘They'll play the school song. They always do.' ‘But-‘ ‘Shut up. You talk too fucking much.' The tip of his cigarette winked peacefully in the dark. She shut. But (oh when this is over you're going to get it buddy maybe you'll go to bed with lover's nuts tonight) her mind ran furiously over his words, storing them. People did not speak to her in such a manner. Her father was a lawyer. It was seven minutes to ten. He was holding the broken pencil in his hand, ready to write, when she touched his wrist lightly, tentatively. ‘Don't . .' ‘What?' ‘Don't vote for us,' she said finally. He raised his eyebrows quizzically. ‘Why not? In for a penny, in for a pound. That's what my mother always says.' (mother) A picture rose in her mind instantly, her mother droning endless prayers to a towering, faceless, columnar God who prowled roadhouse parking lots with a sword of fire in one hand. Terror rose in her blackly, and she had to fight with all her spirit to hold it back. She could not explain her dread, her sense of premonition. She could only smile helplessly and repeat: ‘Don't. Please.' The Honour Society ushers were coming back, collecting folded slips. He hesitated a moment longer, then suddenly scrawled Tommy and Carrie on the ragged slip of paper. ‘For you,' he said. ‘Tonight you go first-class.' She could not reply, for the premonition was on her. her mother's face. The knife slipped from the whetstone, and in an instant it had sliced the cup of her palm below the thumb. She looked at the cut. It bled slowly, thickly, from the open lips of the wound running out of her hand and spotting the worn linoleum of the kitchen floor. Good, then. It was good. The blade had tasted flesh and let blood. She did not bandage it but tipped the flow over the cutting edge, letting the blood dull the blade's edge, then she began to sharpen again, heedless of the droplets which splattered her dress. If thine right eye offend thee, pluck it out If it was a hard scripture, it was also sweet and good. A fitting scripture for those who lurked in the doorway shadows of one-night hotels and in the weeds behind bowling alleys. Pluck it out (oh and the nasty music they play) Pluck it (the girls show their underwear how it sweats how it sweats blood) out The Black Forest cuckoo began to strike ten and (cut her guts out on the floor) if thine right eye offend thee, pluck it out The dress was done and she could not watch the television or take out her books or call Nancy on the phone. There was nothing to do but sit on the sofa facing the blackness of the kitchen window and feel some nameless sort of fear growing in her like an infant coming to dreadful term. With a sigh she began to massage her arms absently. They were cold and prickly. It was twelve after ten and there was no reason, really no reason, to feel that the world was coming to an end. The stacks were higher this time, but they still looked exactly the same. Again, three counts were taken to make sure. Then Vic Mooney went to the mike again. He paused a moment, relishing the blue feel of tension in the air, and then announced simply: `Tommy and Carrie win. By one vote.' Dead silence for a moment, then applause filled the hall again, some of it not without satiric overtones. Carrie drew in a startled, smothered gasp, and Tommy again felt (but for only a second) that weird vertigo in his mind (carrie carrie carrie carrie) that seemed to blank out all thought but the name and image of this strange girl he was with. For a fleeting second he was literally scared shitless. Something fell on the floor with a clink, and at the same instant the candle between them whiffed out. Then Josie and the Moonglows were playing a rock version of Pomp and Circumstance, the ushers appeared at their table (almost magically; all this had been rehearsed meticulously by Miss Geer who, according to rumour, ate slow and clumsy ushers for lunch), a sceptre wrapped in aluminium foil was thrust into Tommy's hand, a robe with a lush dog-fur collar was thrown over Carrie's shoulders, and they were being led down the centre aisle by a boy and a girl in white blazers. The band blared. The audience applauded. Miss Geer looked vindicated. Tommy Ross was grinning bemusedly. They were ushered up the steps to the apron, led across to the thrones, and seated. Still the applause swelled. The sarcasm in it was lost now; it was honest and deep, a little frightening. Carrie was glad to sit down. It was all happening too fast. Her legs were trembling under her and suddenly, even with the comparatively high neck of her gown, her breasts (dirtypillows) felt dreadfully exposed. The sound of the applause in her ears made her feel woozy, almost punch-drunk. Part of her was actually convinced that all this was a dream from which she would wake with mixed feeling of loss and relief. Vic boomed into the mike: ‘The King and Queen of the 1979 Spring Ball – Tommy ROSS and Carrie WHITE' Still applause, swelling and booming and crackling. Tommy Ross in the fading moments of his life now, took Carrie's hand and grinned at her, thinking that Suzie's intuition had been very right. Somehow she grinned back. TOMMY (she was right and i love her well i love this one too this carrie she is beautiful and it's right and i love all of them the light the light in her eyes) and Carrie (can't see them the lights are too bright i can hear them but can't see them the shower remember the shower o momma it's too high i think i want to get down o are they laughing and ready to throw things to point and scream with laughter i can't see them i can't see them it's all too bright) and the beam above them. Both bands, in a sudden and serendipitous coalition of rock and brass, swung into the school song. The audience rose to its feet and began to sing, still applauding. It was ten-o-seven. Billy had just flexed his knees to make the Joints pop. Chris Hargensen stood next to him with increasing aura of nervousness. Her hands played aimlessly along the seams of the jeans she had worn and she was biting the softness of her lower lip, chewing at it, making it a little ragged. ‘You think they'll vote for them?, Billy said softly.